ImmunoFolate
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Advancing the Fight Against ARDS and Lung Cancer

Advancing the Fight Against ARDS and Lung CancerAdvancing the Fight Against ARDS and Lung CancerAdvancing the Fight Against ARDS and Lung Cancer

Rapid Defense Inc. is pioneering folate-based immunotherapy and wellness supplements that harness the body’s innate healing

Learn more about ImmunoFolate™ (ImmunoPterin)

Advancing the Fight Against ARDS and Lung Cancer

Advancing the Fight Against ARDS and Lung CancerAdvancing the Fight Against ARDS and Lung CancerAdvancing the Fight Against ARDS and Lung Cancer

Rapid Defense Inc. is pioneering folate-based immunotherapy and wellness supplements that harness the body’s innate healing

Learn more about ImmunoFolate™ (ImmunoPterin)

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About Us

Pioneering Immunotherapy for Critical Illness and Lung Cancer

Explore ImmunoFolate and ImmunoPterin, Rapid Defense's breakthrough folate- and pterin-based immunotherapies developed to reprogram immune responses in patients suffering from non-small cell lung cancer (NSCLC), acute respiratory distress syndrome (ARDS), pneumonia, sepsis, trauma, and viral infections.

About Rapid Defense

At Rapid Defense, we believe the human body can heal itself, mainly when the immune system works the way it should. That’s why we’re dedicated to developing therapies and wellness supplements that work with the body, not against it.

We focus on folate- and pterin- based immunotherapies, an advanced approach that helps retrain and restore immune function in patients facing severe health challenges. Whether it’s cancer, sepsis, pneumonia, trauma, or ARDS, our treatments are designed to support the body’s natural defenses and improve its response to illness.

We combine medical science with deep care for patient outcomes. With ImmunoFolate and ImmunoPterin, we aim to provide solutions that fight disease and strengthen the body’s healing abilities safely, effectively, and compassionately. We are dedicated to transforming the treatment of immune-related diseases through targeted immunotherapies. 

ImmunoFolate and ImmunoPterin therapies are rooted in immunological science and designed to support immune reprogramming in oncology and critical care settings. We specialize in addressing immune dysfunction at its root, aiming to improve survival and recovery in life-threatening conditions like NSCLC, sepsis, and ARDS.

Our Immunotherapies

ImmunoFolate

A next-generation, folate-based immunotherapy that reprograms immune cell behavior in patients with non-small cell lung cancer (NSCLC). ImmunoFolate enhances immune system function, reduces immunosuppression within the tumor microenvironment, and improves treatment outcomes when used alongside conventional therapies.

Key Hypothesized Benefits:

● Targets folate receptor pathways

● Enhances antigen presentation and T-cell activation

● Reduces tumor-induced immune evasion


ImmunoPterin

ImmunoPterin addresses systemic inflammation and immune dysregulation in acute care scenarios such as ARDS, sepsis, pneumonia, and trauma. This immunotherapy works by modulating cytokine release, supporting immune balance, and reducing the risk of organ damage.

Key Hypothesized Benefits:

● Supports immune homeostasis

● Helps regulate cytokine storms

● Complements critical care protocols

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The Conditions We Target

Rapid Defense's immunotherapies are designed for conditions where immune dysfunction drives disease progression:

● Non-Small Cell Lung Cancer (NSCLC): A leading cause of cancer mortality globally. ImmunoFolate™ supports immune targeting and tumor response.

● Acute Respiratory Distress Syndrome (ARDS) is common in intensive care. ImmunoPterin seeks to control systemic inflammation and lung injury.

● Sepsis: A life-threatening condition involving immune overreaction. Our therapy supports immune modulation.

● Pneumonia: Severe lung infections often escalate into ARDS; ImmunoFolate™ aids in immune response regulation.

● Severe Trauma: Immune dysfunction from trauma leads to secondary complications, which our therapy seeks to mitigate.

Backed by Clinical Research & Innovation

Our therapies are supported by peer-reviewed research, preclinical data, and clinical trial insights.

Highlights:

● ImmunoFolate™ has shown promise in reducing immune escape mechanisms such as indoleamine 2,3 dioxygenase, in NSCLC.

● ImmunoPterin demonstrated cytokine modulation and improved immune response in preclinical ARDS models.

● Mechanism of action studies are available for download at http://linkedin.com/in/phillip-moheno-phd-3852214.

Why Choose Rapid Defense?

● Research-Driven Innovation: Therapies developed from immunological insights

● Targeted Immune Modulation: Not symptom suppression, but immune reprogramming

● Clinical Expertise: Led by a team of experienced immunologists and medical scientists

● Transparent & Ethical: Committed to safety, data transparency, and regulatory compliance

Upcoming Clinical Trial: ARDS (Acute Respiratory Distress Syndrome)

Rapid Defense is launching a $2 million Phase 2 clinical trial to evaluate ImmunoFolate as a potential treatment for ARDS, a critical and often fatal complication of viral pneumonia, sepsis, and trauma.


🔬 The study will assess whether ImmunoFolate can safely reduce inflammation and improve oxygenation in patients suffering from ARDS by modulating cytokine storms at the molecular level.


📍 Trial Summary:


  • Study Population: 100 hospitalized ARDS patients
     
  • Design: Randomized, double-blind, placebo-controlled
     
  • Goal: Improve oxygenation, reduce ventilator use, and save lives
     
  • Budget: $2 million, with partial funding secured and investor participation open
     

📢 We are seeking collaborators, hospital partners, and funding partners to help bring this urgently needed intervention into critical care settings.

A Transformative Immunotherapy for NSCLC

ImmunoFolate Therapeutics by Rapid Defense is launching a first-in-human clinical trial for ImmunoFolate—a novel folate-based immunotherapy designed to reprogram the immune system against non-small cell lung cancer (NSCLC).

We are currently raising $10 million to fund this pivotal clinical program.

🧬 Why ImmunoFolate?

Non-small cell lung cancer remains one of the most lethal forms of cancer worldwide, with limited durable responses to existing immunotherapies. ImmunoFolate offers a first-in-class mechanism that:

  • Stimulates antigen-presenting cells (APCs)
     
  • Enhances T-cell activation
     
  • Operates through natural immune pathways
     
  • Has demonstrated potent anti-tumor effects in preclinical models
     

This immune-modulating approach represents a new frontier in oncology—merging metabolic signaling with precision immunotherapy.

💊 Our Product ImmunoFolate™ — Folate-Based Immune Support

• Clinically inspired formula

• Non-GMO, vegan, and bioavailable

• Designed to support cytokine balance and immune resilience

🧬 Science Behind Rapid Defense

ImmunoFolate™ is based on the hypothesis that pterin and folate derivatives can restore immune homeostasis by modulating cytokines like IL-6, IL-10, IL-12, IFN-γ, and TGF-β; and IDO (Indoleamine 2,3 dioxygenase) impacting immune surveillance, tumor evasion, and inflammation resolution. 

Key Highlights

  • Immunopterin: A novel folate analog with selective immune-modulating activity
  • Preclinical Promise: Evidence suggests potential efficacy against aggressive cancers and chronic inflammation, and infectious diseases
  • Mechanism of Action: Thought to act on antigen-presenting cells and T-regulatory pathways

🧪 Clinical Trial Initiative

Help Us Launch the First-in-Human Study

 We are preparing a Phase 1/2 clinical trials of ImmunoFolate™for patients with ARDS and non-small cell lung cancer and metastatic colorectal cancer. 

Objectives:

  • Establish safety, tolerability, and optimal dosing
  • Measure effects on tumor immune infiltration
  • Evaluate progression-free survival 

✅ Trial protocol developed
✅ Seeking FDA IND clearance
✅ Now raising $10M in seed funding

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🧪 Our Clinical Roadmap

Phase I/II Clinical Trial Objectives:

  • Assess safety and tolerability of ImmunoFolate in ARDS and NSCLC patients
     
  • Establish optimal dosing
     
  • Evaluate immune response and preliminary signs of efficacy
     

Use of Funds:

  • IND-enabling studies and FDA submission
     
  • cGMP manufacturing of clinical-grade ImmunoFolate
     
  • Clinical site selection, patient recruitment, and trial execution
     
  • Biomarker and immunologic response analysis

📈 A Compelling Market Opportunity

  • NSCLC accounts for ~85% of all lung cancer diagnoses
     
  • Global NSCLC immunotherapy market projected to exceed $25B by 2030
     
  • Urgent need for immune-based therapies with novel mechanisms of action for ARDS

How to Get Involved

  • Healthcare Providers: Interested in participating in our ARDS and/or NSCLC trials? Contact Dr. Phillip Moheno.
     
  • Investors & Donors: Help us meet our $2-10M goals to complete the trials. Let’s save lives together.
     
  • Patients & Families: ImmunoFolate will soon be available as a premium immune support supplement—visit our online store.

Donate now
Welcome

Hello

Rapid Defense Inc. is a biopharmaceutical company committed to developing innovative immunotherapy solutions that enhance the immune system's capabilities in combating diseases. Our flagship product, ImmunoFolate, is designed to enhance and modulate immune responses.

Marquis Who's Who Top Scientist Bio

More About Us

Our Vision

Our Vision

Our Vision

 At Rapid Defense, we believe that the future of medicine lies in restoring the body’s own immune intelligence. Our research blends classical biochemistry and immunology into a therapeutic paradigm. 

Leadership

Our Vision

Our Vision

  

  • Dr. Phillip B. Moheno, Ph.D. – Founder & Scientific Director
    Former academic and co-author with Dietmar Fuchs, Ph.D. of Immunopterin: A prospective therapy and preventative to fight COVID-19?
  • Scientific Advisory Board:      [Coming Soon]

Rapid Defense Pitch Deck / Supporting Files


🤝 Partner With Us

We are actively seeking strategic investors, venture partners, and clinical collaborators to join us in advancing this high-impact therapy to the clinic.

If you're an investor, biotech executive, or healthcare advocate passionate about transforming cancer treatment, we invite you to connect with us.

📧 Contact: phil.moheno@rapiddefenseinc.com

Rapid Defense Inc.

PO Box 22840

San Diego, CA 92192

858-344-9778

NSCLC Clinical Trial Budget Estimate II (docx)Download
Immunofolate_NSCLC_Trial_Design_Updated (pdf)Download
Clinical Trial Protocol- ImmunoFolate for the Treatment of ARDS (pdf)Download
Clinical Trial Budget Estimate- ImmunoFolate for ARDS (pdf)Download
Rapid Defense Pitch Deck (pdf)Download

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